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Apoptosis Cell Biology

Studies from E. Saulle et al have provided new data on apoptosis cell biology

Published in Women's Health Weekly, August 23rd, 2007

Data detailed in "Proteasome inhibitors sensitize ovarian cancer cells to TRAIL induced apoptosis" have been presented. According to recent research from Rome, Italy, "In the present study we have explored the sensitivity of ovarian cancer cells to TRAIL and proteasome inhibitors. Particularly, we have explored the capacity of proteasome inhibitors to bypass TRAIL resistance of ovarian cancer cells."

"For these studies we have used the A2780 ovarian cancer cell line and its chemoresistant derivatives A2780/DDP and A2780/ADR, providing evidence that: (i) the three cell lines are either scarcely sensitive (A2780 and A2780/ADR) or moderately sensitive (A2780/DDP) to the...

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