Breast Cancer Genetics
Research from University of Pisa in the area of breast cancer genetics published
Published in Women's Health Weekly, August 23rd, 2007
Researchers detail in "Identification of novel alternatively spliced BRCA1-associated RING domain (BARD1) messenger RNAs in human peripheral blood lymphocytes and in sporadic breast cancer tissues," new data in breast cancer. According to a study from Pisa, Italy, "BARD1 (BRCA1-associated RING domain) is the dominant binding partner of BRCA1 in vivo. The BARD1 gene has been reported to be mutated in a subset of breast and ovarian cancer patients and BARD1 germ-line mutations have been identified in breast cancer patients negative for BRCA1 or BRCA2 gene alterations."
"In the present study, we show by RT-PCR and direct sequencing analysis the occurrence of seven novel...
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