Breast Cancer Prevention
New breast cancer prevention study findings recently were published by researchers at Georgetown University, Lombardi Comprehensive Cancer Center
Published in Women's Health Weekly, August 30th, 2007
A report, "Epidermal growth factor receptor tyrosine phosphorylation and signaling controlled by a nuclear receptor coactivator, amplified in breast cancer 1," is newly published data in Cancer Research. "The steroid receptor coactivator amplified in breast cancer 1 (AIB1) as well as epidermal growth factor receptor (EGFR) family members are frequently overexpressed in epithelial tumors, and their expression is associated with poor prognosis. However, a direct role of AIB1 in EGF signaling has not been determined," researchers in the United States report.
"To address this, we reduced endogenous AIB1 levels using RNA interference in lung, breast, and pancreatic...
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