Breast Cancer Risk Factors
Recent findings from University of Southern California, Department of Preventive Medicine highlight research in breast cancer risk factors
Published in Women's Health Weekly, September 20th, 2007
Research findings, "Prospective study of grapefruit intake and risk of breast cancer in postmenopausal women: the Multiethnic Cohort Study," are discussed in a new report. "In vitro and in vivo studies have shown that cytochrome P450 3A4 (CYP3A4) is involved in the metabolism of oestrogens. There is evidence that grapefruit, an inhibitor of CYP3A4, increases plasma oestrogen concentrations," investigators in the United States report.
"Since it is well established that oestrogen is associated with breast cancer risk, it is plausible that regular intake of grapefruit would increase a woman's risk of breast cancer. We investigated the association of grapefruit intake with...
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