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Female Infertility Genetics

Research from Karolinska University, Institute of Molecular and Cell Biology in female infertility genetics provides new insights

Published in Women's Health Weekly, September 20th, 2007

Fresh data on female infertility are presented in the report "Allelic estrogen receptor 1 (ESR1) gene variants predict the outcome of ovarian stimulation in in vitro fertilization." According to recent research from Stockholm, Sweden, "The outcome of in vitro fertilization (IVF) depends substantially on the effectiveness of controlled ovarian hyperstimulation (COH) induced by administration of follicle-stimulating hormone (FSH). In COH, endogenously produced estrogens extend the action of FSH in stimulating folliculogenesis."

"We determined the associations between genetic variations in estrogen receptor ESR1 and ESR2 genes and etiology of female infertility, and...

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