Breast Cancer

New breast cancer data have been reported by scientists at Albany Medical College, Medical College

Published in Women's Health Weekly, October 11th, 2007

"Tumor invasion and metastasis are the main causes of death from cancer. Epithelial to mesenchymal transition (EMT) is a determining step for a cancer cell to progress from a noninvasive to invasive state," scientists in the United States report.

"Kruppel-like factor 8 (KLF8) plays a key role in oncogenic transformation and is highly overexpressed in several types of invasive human cancer, including breast cancer. To understand the role of KLF8 in regulating the progression of human breast cancer, we first established stable expression of KLF8 in an immortalized normal human breast epithelial cell line. We found that KLF8 strongly induced EMT and enhanced motility and...

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Source: Women's Health Weekly (2007-10-11)

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