Angiogenesis

New research on angiogenesis from J.M.A. Pijnenborg and co-authors summarized

Published in Women's Health Weekly, October 25th, 2007

According to a study from Netherlands, "'Tumor hypoxia can trigger the induction of angiogenesis. High microvessel density (MVD) as well as hypoxia-inducible factor-1 alpha (HIF-1 alpha) have been related to recurrent disease and tumor aggressiveness, respectively."

"In this study, MVD and hypoxic status were investigated in primary and recurrent endometrial carcinomas. A total of 65 primary tumors of patients with recurrent endometrial carcinoma (n = 40), and without recurrent endometrial carcinoma (n = 25) were studied. Immunohistochemical analysis was performed on paraffin-embedded tumor tissue. MVD was determined by quantitative analysis of CD31/FVIII positive...

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Source: Women's Health Weekly (2007-10-25)

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