Angiogenesis

Immune cells promote blood vessel formation in mouse endometriosis

Published in Women's Health Weekly, November 1st, 2007

A discovery in mice of immune cells that promote the formation of new blood vessels could lead to new treatments for endometriosis, a painful condition associated with infertility that affects up to 15 percent of women of reproductive age.

The formation of new blood vessels, or angiogenesis, is known to encourage the growth of tumors and endometriosis lesions. A team led by Ofer Fainaru, MD, PhD, a research associate in the Vascular Biology Program at Children's Hospital Boston and Harvard Medical School, found that dendritic cells—highly specialized immune cells—help trigger angiogenesis in a mouse model of endometriosis. Their findings were published online last month...

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Source: Women's Health Weekly (2007-11-01)

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