Sjogren Syndrome
Studies from University of Birmingham provide new data on Sjogren syndrome
Published in Women's Health Weekly, November 15th, 2007
According to recent research published in the journal Pediatric Nephrology, "We describe two adolescents who presented with end-stage renal failure and clinical features suggestive of Sjogren's syndrome (SS). They both demonstrated severe, chronic, tubulointerstitial inflammation on renal biopsy, high-titre antinuclear antibodies, high immunoglobulin A and G concentrations, positive anti-SSA and anti-SSB antibodies, and negative anti-double-stranded DNA antibodies."
"One had subjective and objective evidence of the sicca complex (dry eyes and/or dry mouth) and fulfilled the commonly accepted SS consensus criteria. The other showed no evidence of the sicca complex...
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