Breast Cancer

Data on breast cancer published by Y. Zhang and colleagues

Published in Women's Health Weekly, November 22nd, 2007

According to recent research from Beijing, People's Republic of China, "C-Jun/AP-I has been linked to invasive properties of aggressive breast cancer. Recently, it has been reported that overexpression of c-Jun in breast cancer cell line MCF-7 resulted in increased AP-I activity, motility and invasiveness of the cells in vitro and tumor formation in nude mice."

"However, the role of c-Jun in metastasis of human breast cancer in vivo is currently unknown To further investigate the direct involvement of c-Jun in tumorigenesis and metastasis, in the present study, the effects of c-Jun overexpression were studied in both in vitro and in nude mice Ectopic overexpression of...

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Source: Women's Health Weekly (2007-11-22)

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