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Breast Cancer

McGill researchers link enzyme to breast cancer malignancy

Published in Women's Health Weekly, December 20th, 2007

This release is available in French. McGill University researchers have uncovered the crucial role played by the enzyme focal adhesion kinase (FAK) in the onset of breast cancer. The research, led by Dr. William Muller – along with colleagues from McGill and the Beatson Institute for Cancer Research in Scotland – was published the week of November 26 in the Proceedings of the National Academy of Sciences (PNAS). The study's first author is Dr. Hicham Lahlou, a post-doctoral fellow in Dr. Muller's lab.

Using transgenic mice with pre-existing cancers, the McGill team was able to disable the function of FAK in the mammary gland. "When we did that, we basically blocked...

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