Breast Cancer

New study reveals for first time how BRCA1 mutations cause breast cancer

Published in Women's Health Weekly, December 27th, 2007

An international team of researchers led by Columbia University Medical Center’s Herbert Irving Comprehensive Cancer Center and Sweden’s Lund University has, for the first time, revealed how mutations in the BRCA1 gene lead to breast cancer. Findings show that one way BRCA1 mutations cause cancer is by knocking out a powerful tumor suppressor gene known as PTEN.

The new study will be published online on the Nature Genetics website on Dec. 9, 2007: http://www.nature.com/ng. It will appear in the January print issue of this journal. The study was led by Ramon Parsons, M.D., Ph.D., the Avon Foundation Professor of Medicine and Pathology at Columbia University College of...

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Source: Women's Health Weekly (2007-12-27)

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