Polycystic Ovarian Syndrome

New polycystic ovarian syndrome findings from T. Baba and co-researchers published

Published in Women's Health Weekly, January 3rd, 2008

According to a study from Sapporo, Japan, "(PCOS). We hypothesized that insulin receptor substrate-1 (IRS-1) Gly972Arg polymorphism and/or ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) Lysl 2 1 Gln polymorphism predisposes women to PCOS and that these polymorphisms also affect anthropometric variables, glucose metabolism and androgen synthesis."

"To test those ideas, we studied the genotypes, indexes of insulin resistance, and hormone profiles in 123 Japanese women with PCOS and 3 80 healthy Japanese controls. We found that there were significantly more IRS-1 972Arg carriers among the PCOS patients than among the healthy controls (10.6% vs. 4.8%, p=0.029),...

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Source: Women's Health Weekly (2008-01-03)

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