Breast Cancer

Researchers from Rutgers University provide details of new studies and findings in the area of breast cancer

Published in Women's Health Weekly, January 31st, 2008

"Gene expression analysis has identified biologically relevant subclasses of breast cancer. However, most classification schemes do not robustly cluster all HER2+ breast cancers, in part due to limitations and bias of clustering techniques used," scientists in the United States report.

"In this article, we propose an alternative approach that first separates the HER2+ tumors using a gene amplification signal for Her2/neu amplicon genes and then applies consensus ensemble clustering separately to the HER2+ and HER2-clusters to look for further substructure. We applied this procedure to a microarray data set of 286 early-stage breast cancers treated only with surgery and...

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Source: Women's Health Weekly (2008-01-31)

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