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Enzyme Research

Research on enzyme research discussed by scientists at University of California, Center for Neurovisceral Sciences and Women's Health

Published in Women's Health Weekly, January 31st, 2008

A report, 'Comparing analgesia and mu-opioid receptor internalization produced by intrathecal enkephalin: requirement for peptidase inhibition,' is newly published data in Neuropharmacology. According to a study from the United States, "Opioid receptors in the spinal cord produce strong analgesia, but the mechanisms controlling their activation by endogenous opioids remain unclear. We have previously shown in spinal cord slices that peptidases preclude mu-opioid receptor (MOR) internalization by opioids."

"Our present goals were to investigate whether enkephalin-induced analgesia is also precluded by peptidases, and whether it is mediated by MORs or delta-opioid...

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