Life Sciences
Reports outline life sciences research from G.R. Bolduc and colleagues
Published in Women's Health Weekly, January 31st, 2008
Research findings, 'The group B streptococcal alpha C protein binds alpha1beta1-integrin through a novel KTD motif that promotes internalization of GBS within human epithelial cells,' are discussed in a new report. "Group B Streptococcus (GBS) is the leading cause of bacterial pneumonia, sepsis and meningitis among neonates and a cause of morbidity among pregnant women and immunocompromised adults. GBS epithelial cell invasion is associated with expression of alpha C protein (ACP)," investigators in the United States report.
"Loss of ACP expression results in a decrease in GBS internalization and translocation across human cervical epithelial cells (ME180). Soluble ACP...
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