Published in Women's Health Weekly, February 7th, 2008
"Obese and spontaneously hypertensive SHR.Cg-Lepr(cp)/NDmcr (cp/cp) rats exhibit phenotypic features that resemble metabolic syndrome. 2. As an initial approach in defining the roles of the sympathetic nervous system and hypothalamic-pituitary-adrenal axis in the mechanism of metabolic syndrome, we examined the gene expression of the adrenoreceptors (alpha(1A), alpha(1B), alpha(1D), alpha(2A), alpha(2B), alpha(2C), beta(1), beta(2) and beta(3)) and the adrenocorticotrophin receptor melanocortin 2 receptor (mc2r) in various tissues from cp/cp rats using real-time reverse transcription-polymerase chain reaction. 3. In cp/cp...
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