Cancer Gene Therapy
Researchers from Soochow University report on findings in cancer gene therapy
Published in Women's Health Weekly, February 14th, 2008
Researchers detail in 'Growth suppression and radiosensitivity increase by HMGB1 in breast cancer,' new data in cancer gene therapy. "HMGB1 (high-mobility group box-1) is a nuclear protein containing a consensus RB (retinoblastoma)-binding LXCXE motif. In this study, we studied the potential association of HMGB1 and RB and the in vitro and in vivo activities of HMGB1 in human breast cancer cells," scientists in Suzhou, People's Republic of China report.
"The protein-protein interaction was determined by immunoprecipitation-Western blotting and glutathione-S-transferase capture assays; cell growth and radiosensitivity were examined by cell counts, MTT assay, and...
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