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Women's Health Weekly

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Angiogenesis



Study results from University of Birmingham provide new insights into angiogenesis



March 13th, 2008

"Over-expression of angiogenic growth factors and their receptors, and high levels of these molecules in the blood, are a common feature of cancer although the relationships between cell expression and plasma levels are unknown. We hypothesized a significant correlation between the expression and cellular distribution of vascular endothelial growth factor (VEGF), its receptor Flt-1, and the angiopoietin receptor Tie-2 with levels of these molecules in the plasma," scientists in Birmingham, the United Kingdom report.

"The tissue expression of VEGF, Flt-1, and Tie-2 were investigated by immunohistochemistry, and plasma levels assessed by enzyme-linked immunosorbent assay...


Source: Women's Health Weekly (2008-03-13)

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