Women's Health Weekly
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Ductal Carcinoma in Situ
Reports from Sahlgrenska University highlight recent research in ductal carcinoma in situ
March 13th, 2008
"The aim of the present work was to explore signal transduction pathways used in the regulation of S100A7 ( psoriasin). Members of the S100 gene family participate in many important cellular functions," scientists writing in the journal BMC Cancer report. "Psoriasin, S100A8 ( calgranulin A) and S100A9 ( calgranulin B) are expressed in ductal carcinoma in situ ( DCIS), as well as in the hyperproliferative skin disease, psoriasis. In the latter condition, a disturbance in the STAT pathway has recently been reported. This pathway is implicated in the regulation of IFN-gamma, widely recognized as a key cytokine in psoriasis. IFN-gamma also exerts anti-tumor action in...
Source: Women's Health Weekly (2008-03-13)
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