Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Gastric Cancer
Investigators at Catholic University, Medical Department zero in on gastric cancer
March 13th, 2008
According to a study from Seoul, South Korea, "Cell death deregulation is a hallmark of human cancers. BNIP3 was initially identified as a proapoptotic member of the Bcl-2 family and plays an important role in apoptosis, necrosis and autophagy." "The aim of this study was to see whether alterations of BNIP3 protein expression and somatic mutation of the BNIP3 gene are characteristics of human cancers. We analyzed the expression of BNIP3 protein in 60 gastric adenocarcinomas by immunohistochemistry. In addition, we analyzed BNIP3 mutation in the DNA sequences encoding BH3 (Bcl-2 homology3) and TM (transmembrane) domains that are important in the cell death function of...
Source: Women's Health Weekly (2008-03-13)
|
