Women's Health Weekly
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Pharmacokinetics
Researchers at State University of New York target pharmacokinetics
March 13th, 2008
According to recent research published in the journal Molecular Pharmaceutics, "Little is known regarding pharmacokinetic (PK) or pharmacodynamic interactions of flavonoids with each other: this is of significance since multiple flavonoids are present in the diet and in dietary supplements. Our objective was to determine the effect of quercetin and (+epigallocatechin-3-gallate (EGCG), major flavonoids present in the diet, on the PK and bioavailability of biochanin A, a flavonoid with chemopreventive properties." "BCA was administered to rats intravenously (5 mg/kg) or orally (116.67 or 50 mg/kg) with or without concomitant EGCG and quercetin. In vitro studies...
Source: Women's Health Weekly (2008-03-13)
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