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Women's Health Weekly

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Breast Cancer



Scientists at East Carolina University discuss research in breast cancer



March 13th, 2008

Data detailed in 'Induction and processing of complex DNA damage in human breast cancer cells MCF-7 and nonmalignant MCF-10A cells' have been presented. According to a study from the United States, "Oxidatively induced stress and DNA damage have been associated with various human pathophysiological conditions, including cancer and aging. Complex DNA damage such as double-strand breaks (DSBs) and non-DSB bistranded oxidatively induced clustered DNA lesions (OCDL) (two or more DNA lesions within a short DNA fragment of 1-10 bp on opposing DNA strands) are hypothesized to be repair-resistant lesions challenging the repair mechanisms of the cell."

"To evaluate the induction...


Source: Women's Health Weekly (2008-03-13)

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