Breast Cancer Genetics
New breast cancer genetics study results from University of Minho, Life and Health Sciences Research Institute described
Published in Women's Health Weekly, March 13th, 2008
New research, 'Importance of TP53 codon 72 and intron 3 duplication 16bp polymorphisms in prediction of susceptibility on breast cancer,' is the subject of a report. "TP53 is one of major tumor suppressor genes being essential in preservation of genome integrity. Two very common polymorphisms have been demonstrated to contribute to cancer susceptibility and tumor behaviour," scientists in Braga, Portugal report.
"The purpose of this study was to evaluate the role of Arg72Pro and PIN3 Ins16bp polymorphisms in TP53 gene as genetic susceptibility and predictive markers to breast cancer. We analysed DNA samples from 264 breast cancer patients and 440 controls, for TP53...
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