Women's Health Weekly
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Breast Cancer
New breast cancer study findings reported from S. Hassan and co-authors
March 20th, 2008
According to a study from Montreal, Canada, "Homing of breast cancer cells to metastatic sites may be regulated by the production of stromal cell-derived factor (SDF)-1 by specific target organs, which attracts CXCR4-expressing breast cancer cells. We investigated the value of SDF-1 as a predictive blood marker of distant metastasis in breast cancer, together with a common polymorphism of SDF-1, SDF-1-3'A." "Plasma samples were collected prospectively for 270 consecutive primary breast cancer patients with a median follow-up of 3.3 years. Plasma SDF-1 levels were measured using an ELISA, and the polymorphism was identified via PCR-RFLP analysis. Plasma SDF-1 levels were...
Source: Women's Health Weekly (2008-03-20)
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