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Women's Health Weekly

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Breast Cancer



Studies from University of Alcala yield new information about breast cancer



March 20th, 2008

According to a study from Spain, "Previous studies have shown that vasoactive intestinal peptide (VIP) and its receptors (VPAC(1) and VPAC(2) receptors) are involved in promotion and growth of many human tumours including breast cancer. Here we investigated whether VIP regulates the expression of the main angiogenic factor, vascular endothelial cell growth factor (VEGF) in human oestrogen-dependent (T47D) and oestrogen-independent (MDA-MB-4687) breast cancer cells."

"Semiquantitative and quantitative real-time RT-PCRs were used at rnRNA level whereas enzyme immunoanalysis was performed at protein level. Both cancer cell lines expressed VIP and VPAC(1) (but not VPAC(2))...


Source: Women's Health Weekly (2008-03-20)

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