Women's Health Weekly
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Breast Cancer
New breast cancer data have been reported by scientists at University of California
March 27th, 2008
"Purpose of review Mammary epithelial proliferation is controlled by the ovarian hormones estrogen and progesterone. Although BRCA1 (breast cancer 1, early onset) is ubiquitously expressed, women with BRCA1 mutations have a propensity to develop tumors in tissues sensitive to ovarian hormone," scientists writing in the journal Current Opinion in Obstetrics & Gynecology report. "An understanding of the tissue-specific function of the BRCA1-encoded protein (BRCA1) provides additional insight that may improve cancer risk reduction in BRCA1 mutation carriers. Recent findings Studies using mouse models have shown that BRCA1 regulates the abundance of progesterone...
Source: Women's Health Weekly (2008-03-27)
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