Women's Health Weekly
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Breast Cancer
Reports summarize breast cancer study results from Pomeranian Medical University
March 27th, 2008
According to a study from Szczecin, Poland, "Nucleolin (NU) can be found in the nucleus in aggregates and in a diffused form. The expression and distribution of these two intranuclear pools of nucleolin was compared in estrogen receptor (ER)-positive and -negative invasive ductal breast carcinomas in relation to cell cycle phases." "Using a laser scanning cytometer NU was measured within the whole nucleus, within nucleolin aggregates (NUA) and within the NUA-free katyoplasm. The G(1)-, S- and G(2)M-phase cell subpopulations were distinguished on DNA histograms. The nuclei of ER-positive and ER-negative breast carcinomas in the G(2)M-phase differed in the expression of...
Source: Women's Health Weekly (2008-03-27)
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