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Breast Cancer

Study results from C. Catania and colleagues broaden understanding of breast cancer

Published in Women's Health Weekly, March 27th, 2008

"Trastuzumab M combined with i.v. vinorelbine (i.v.VNR) is an active regimen for patients with advanced breast cancer (ABC). In order to further improve quality of life of patients undergoing treatment for ABC, a new regimen using oral vinorelbine (oVNR) (d1 + d3) plus q3wks T was tested (ToVNR)," investigators in Milan, Italy report.

"Thirty-nine patients with ABC, human epidermal growth factor receptor 2/neu 3+ or FISH positive received 288 treatment cycles with T 6 mg/kg (loading dose, 8 mg/kg) on d1 and oVNR 55 mg/m(2) on d1 + d3, q3wks until disease progression or unacceptable toxicity. Thirty-seven patients and 286 treatment cycles were evaluated (two patients...

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