Women's Health Weekly
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Osteosarcoma
Same process discovered to both form skeleton and protect it for life
March 27th, 2008
A protein signaling pathway recently discovered to guide the formation of the skeleton in the fetus also keeps bones strong through adult life, according to two papers published recently in the journal Nature Medicine. Furthermore, the same mechanism may be at the heart of osteoporosis, where too little bone is made over time, and bone cancer, where uncontrolled bone growth contributes to tumors. Lastly, the results argue that an experimental Alzheimer's drug may also be useful against bone cancer. Human cells must be able to send signals that switch life processes on and off as they form the fetus, and later, to maintain the integrity of adult tissue. Notch proteins...
Source: Women's Health Weekly (2008-03-27)
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