Women's Health Weekly
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Breast Cancer
Findings from L. Mellemkjaer and co-researchers advance knowledge in breast cancer
April 3rd, 2008
"The protein encoded by the CHEK2 gene is involved in cellular repair of DNA damage. The truncating mutation, CHEK2* 1100delC, seems to increase the risk for breast cancer," scientists in Copenhagen, Denmark report. "We investigated whether the CHEK2* 1100delC mutation carrier status increases the risk for asynchronous contralateral breast cancer (CBC) and whether it interacts with radiation therapy (RT) or chemotherapy in regard to CBC risk. The germline mutation frequency was assessed in 708 women with CBC and 1395 women with unilateral breast cancer (UBC) in the Women's Environment, Cancer and Radiation Epidemiology (WECARE) Study whose first primary breast cancer...
Source: Women's Health Weekly (2008-04-03)
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