Women's Health Weekly
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Breast Cancer
Findings from Princess Margaret Hospital provide new insights into breast cancer
April 3rd, 2008
According to a study from Toronto, Canada, " First- and second-line chemotherapy with anthracyclines and taxanes in metastatic breast cancer yield a modest improvement in survival with potentially significant toxicity. Subsequent lines of chemotherapy yield response rates of 20-25%, with an unknown impact on survival." "Perifosine, an oral alkylphospholipid structurally related to miltefosine, has marked activity against breast cancer cell lines and xenograft models, with broad spectrum cellular effects. Objectives To determine the efficacy and toxicity of perifosine in patients with metastatic breast cancer patients after up to 2 lines of prior chemotherapy for...
Source: Women's Health Weekly (2008-04-03)
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