Women's Health Weekly
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Breast Cancer
Investigators at Linkoping University publish new data on breast cancer
April 3rd, 2008
According to a study from Sweden, "In situ synthesis of estrogens is believed to be of great importance for the progression of breast cancer. In postmenopausal women most estrogens are synthesized in peripheral hormone-target tissues from circulating precursor steroids, by the enzymes involved in formation of active estrogens." "One of the enzymes involved in this process is 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) type 1. This enzyme catalyzes the interconversion of estrone (E1) to the biologically more potent estradiol (E2). The gene coding for 17 beta-HSD type 1 (HSD17B1) is located at 17q12-21. The aim of this study was to investigate altered gene copy...
Source: Women's Health Weekly (2008-04-03)
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