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Women's Health Weekly

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Breast Cancer



New breast cancer study findings reported from University of California



April 3rd, 2008

"In mice bearing human breast cancer xenografts, we examined the biodistribution of F-18-fluorocyclophosphamide (F-18-F-CP) to evaluate its potential as a noninvasive prognostic tool for predicting the resistance of tumors to cyclophosphamide therapy. F-18-F-CP was synthesized as we recently described, and PET data were acquired after administration of F-18-F-CP in mice bearing human breast cancer xenografts (MCF-7 cells)," researchers in the United States report.

"Tracer biodistribution in reconstructed images was quantified by region-of-interest analysis. Distribution was also assessed by harvesting dissected organs, tumors, and blood, determining F-18 content in each...


Source: Women's Health Weekly (2008-04-03)

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