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Women's Health Weekly

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Osteoporosis



Gene variants associated with increased risk of bone fractures, low bone mineral density



April 3rd, 2008

Results from a large study indicate that variants of the gene LRP5 are associated with a significant increase in the risk of fractures, by up to 20 percent, and lower levels of bone mineral density in the spine and hip, according to a study in the March 19 issue of JAMA, a theme issue on Genetics and Genomics.

Joyce B. J. van Meurs, Ph.D., of Erasmus MC, Rotterdam, the Netherlands, presented the findings of the study at a JAMA media briefing at the National Press Club in Washington, D.C.

Osteoporosis is characterized by low bone mineral density (BMD), deterioration of bone and increased risk for fractures. Studies have shown that genetic factors...


Source: Women's Health Weekly (2008-04-03)

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