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Myasthenia Gravis Therapy

Study findings from Uppsala University, Department of Clinical Neurophysiology broaden understanding of myasthenia gravis therapy

Published in Women's Health Weekly, April 3rd, 2008

A new study, 'Electrophysiological signs and the prevalence of adverse effects of acetylcholinesterase inhibitors in patients with myasthenia gravis,' is now available. "The aim of this prospective study was to assess whether extra discharges (EDs), sometimes following the compound muscle action potential, could be used as a neurophysiological indicator of overdose of acetylcholinesterase inhibitors (AChEIs) in patients with myasthenia gravis (MG). The characteristics and frequency of EDs were explored and the correlation of EDs with cholinergic side effects was also determined," scientists in Uppsala, Sweden report.

"Twenty-two MG patients (14 women, 8 men; 61...

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