Women's Health Weekly
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Breast Cancer
Studies from University of Bergen yield new information about breast cancer
April 3rd, 2008
In this recent report, researchers in Bergen, Norway conducted a study "To study the relationship between basal-like breast cancers, epidermal growth factor receptor (EGFR) and candidate stem cell markers (BMI-1, EZH2, Oct-4) in a population-based setting. Immunohistochemistry was evaluated in a series of 190 breast cancers." "Basal-like phenotype (BLP) 1-5 was found in 4.3-14.3% of cases. EGFR was expressed in 9% of cases and associated with cytokeratin (CK) 5 and P-cadherin positivity, but not with survival; 28% of CK5+ cases were EGFR+. On multivariate analysis, basal-like differentiation and lymph node status were independent prognostic factors of comparable...
Source: Women's Health Weekly (2008-04-03)
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