Cervical Cancer

Reports from F. Dehdashti et al highlight recent research in cervical cancer

Published in Women's Health Weekly, April 3rd, 2008

"Tumor hypoxia indicates a poor prognosis. This study was undertaken to confirm our prior pilot results showing that pretreatment tumor hypoxia demonstrated by PET with Cu-60-labeled diacetyl-bis(N-4-methylthiosemicarbazone) (Cu-60-ATSM) is a biomarker of poor prognosis in patients with cervical cancer," scientists in the United States report.

"Thirty-eight women with biopsy-proved cervical cancer underwent Cu-60-ATSM PET before the initiation of radiotherapy and chemotherapy. 60Cu-ATSM uptake was evaluated semiquantitatively as the tumor-to-muscle activity ratio (T/M). A log-rank test was used to determine the cutoff uptake value that was strongly predictive of...

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Source: Women's Health Weekly (2008-04-03)

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