Women's Health Weekly
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Angiogenesis
Data on angiogenesis detailed by researchers at Technical University of Munich
April 3rd, 2008
According to recent research from Munich, Germany, "The integrin alpha(v)beta(3) is a key player in angiogenesis and metastasis. Our aim was to study the uptake patterns of the alpha(v)beta(3)-selective PET tracer F-18-galacto-RGD in invasive ductal breast cancer." "Sixteen patients with primary (n = 12) or metastasized breast cancer (n = 4) were examined with F-18-galacto-RGD PET. Standardized uptake values (SUVs) were derived by region-of-interest analysis, and immunohistochemistry of (x (33 expression was performed (n = 5). F-18-Galacto-RGD PET identified all invasive carcinomas, with SUVs from 1.4 to 8.7 (mean +/- SD, 3.6 +/- 1.8; tumor-to-blood and tumor-to-muscle...
Source: Women's Health Weekly (2008-04-03)
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