Women's Health Weekly
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Breast Cancer
Reports outline breast cancer study findings from D. Voduc and colleagues
April 10th, 2008
According to a study from Vancouver, Canada, "GATA-3 is a transcription factor involved in human growth and differentiation. Gene expression profiling has shown that GATA-3 is highly expressed in the Luminal A subtype of breast cancer." "A recent study found GATA-3 to be associated with favorable breast cancer pathologic features, including negative lymph node and positive estrogen receptor (ER) status. GATA-3 levels were also found to be an independent prognostic marker, with low expression predicting for breast cancer recurrence. Our case series consists of 3,119 cases of invasive breast cancer in which GATA-3 expression was assessed by immunohistochemistry on tissue...
Source: Women's Health Weekly (2008-04-10)
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