Women's Health Weekly
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Breast Cancer
Research from National Taiwan University broadens understanding of breast cancer
April 10th, 2008
"Metaplastic carcinoma of the breast (MCB) is a poorly understood subtype of breast cancer. It is generally characterized by the coexistence of ductal carcinomatous and transdifferentiated sarcomatous components, but the underlying molecular alterations, possibly related to epithelial-mesenchymal transition (EMT), remain elusive," researchers in Taipei, Taiwan report. "We performed transcriptional pro. ling using half-a-genome oligonucleotide microarrays to elucidate genetic profiles of MCBs and their differences to those of ductal carcinoma of breasts (DCBs) using discarded specimens of four MCBs and 34 DCBs. Unsupervised clustering disclosed distinctive expression...
Source: Women's Health Weekly (2008-04-10)
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