Women's Health Weekly
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Carcinoma
Studies from National Cheng-Kung University provide new data on carcinoma
April 10th, 2008
According to a study from Tainan, Taiwan, "The ribosomal acidic P0 protein, an essential component of the eukaryotic ribosomal stalk, was found to interact with the helix-loop-helix protein human Grap2 and cyclin D interacting protein (GCIP)/D-type cyclin-interacting protein 1/human homolog of MAID protein. Using in vivo and in vitro binding assays, we show that P0 can interact with the N and C termini of GCIP via its N-terminal 39-114 amino-acid residues." "Although the P0-GCIP complex was detected mainly in cytoplasmic fraction, polysome pro. le analysis indicated that the P0-GCIP complex did not coelute with either polysomes or 60S ribosomes, suggesting that GCIP...
Source: Women's Health Weekly (2008-04-10)
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