Women's Health Weekly
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Chlamydia
Study findings on chlamydia are outlined in reports from Shanghai Jiao Tong University
April 10th, 2008
According to recent research from Shanghai, People's Republic of China, "Single nucleotide polymorphisms (SNPs) provide a great opportunity for the study of human disease and bacterial drug resistance. However, many SNP typing techniques require dedicated instruments and high cost." "Here, we develop a novel method for SNP genotyping based on specific cleavage properties of RNase HII from Chlamydia pneumoniae (CpRNase HII), termed the ''CpRNase HII-based method.'' CpRNase HII cleaves the DNA-rN(1)-DNA/DNA duplex at the 5'-side of the ribonucleotide (rN(1) = one ribonucleotide). Moreover, the cleavage efficiencies of the perfectly matched DNA-rN(1)DNA/DNA duplexes are...
Source: Women's Health Weekly (2008-04-10)
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