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Women's Health Weekly

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Breast Cancer



New breast cancer study findings have been published by scientists at University of Oxford



April 10th, 2008

"The prognosis for patients with estrogen receptor (ER)-positive breast cancer has improved significantly with the prescription of selective ER modulators (SERMs) for ER-positive breast cancer treatment. However, only a proportion of ER-positive tumors respond to SERMs, and resistance to hormonal therapies is still a major problem," scientists writing in the journal Genes Chromosomes & Cancer report.

"Detailed analysis of published microarray studies revealed a positive correlation between overexpression of the drug metabolizing enzyme arylamine N-acetyl-transferase type I (NATI) and ER positivity, and increasing evidence supports a biological role for NATI in...


Source: Women's Health Weekly (2008-04-10)

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