Women's Health Weekly
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Breast Cancer
Reports outline breast cancer study results from University of Massachusetts, Medical Department
April 17th, 2008
"The beta 4 integrin has been implicated in functions associated with the genesis and progression of carcinomas based on data obtained from cell lines and mouse models. Data on its expression and relevance to human carcinomas, however, are relatively scant," scientists writing in the journal Clinical Cancer Research report. "The aim of this study was to assess its expression and prognostic significance in human breast carcinomas. We integrated data on beta 4 expression from multiple gene profiling studies of breast tumors of known clinical outcome with immunohistochemical analysis of 105 breast carcinomas, and we identified genes whose expression correlates with...
Source: Women's Health Weekly (2008-04-17)
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