Women's Health Weekly
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Breast Cancer
Study results from L.B. Thorne and colleagues in the area of breast cancer published
April 17th, 2008
According to a study from Canada, "MI-ER1 is a novel transcriptional regulator that plays a critical role in embryonic development and is differentially expressed in breast carcinoma. The MI-ER1 protein sequence is highly conserved among species, with 95% identity between mouse and humans and 72% between Xenopus and mouse." "There are two major protein isoforms, MI-ER1 alpha and MI-ER1 beta, which differ in the sequence of their C-terminus. MI-ER1 alpha is of particular interest because it contains a consensus LXXLL nuclear receptor interaction motif and the current study was undertaken to determine the expression pattern of MI-ER1 alpha protein in adult mouse tissues....
Source: Women's Health Weekly (2008-04-17)
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