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Women's Health Weekly

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Chlamydia



New chlamydia study findings have been reported by researchers at Autonomous University



April 17th, 2008

"A strategy for the stable expression of proteins, or large protein fragments, from Chlamydia trachomatis into human cells was designed to identify bacterial epitopes endogenously processed and presented by HLA-B27. Fusion protein constructs in which the green fluorescent protein gene was placed at the 5'-end of the bacterial DNA primase gene or some of its fragments were transfected into B(star)2705-C1R cells," scientists writing in the journal Molecular & Cellular Proteomics report.

"One of these constructs, including residues 90-450 of the bacterial protein, was stably and efficiently expressed. Mass spectrometry-based comparative analysis of HLA-B27-bound...


Source: Women's Health Weekly (2008-04-17)

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