Women's Health Weekly
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Breast Cancer
Findings from Seoul National University advance knowledge in breast cancer
April 24th, 2008
In this recent article published in the Journal of Clinical Pathology, scientists in South Korea conducted a study "To investigate the effect of polysomy 17 on HER-2 status as evaluated by immunohistochemistry (IHC), dual-colour fluorescence in situ hybridisation (FISH) and chromogenic in situ hybridisation (CISH). Dual-probe FISH and single-probe CISH were performed to detect HER-2 gene amplification, and IHC to detect HER-2 expression, on 309 invasive breast cancers." "Polysomy 17 was detected in 32.0% of the total number of breast cancers; it was detected in 12.3% of the IHC 0 or 1+ cases, 42.8% of the IHC 2+ cases and 66.0% of the IHC 3+ cases (p <...
Source: Women's Health Weekly (2008-04-24)
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