Women's Health Weekly
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Breast Cancer
Investigators at University of Nancy target breast cancer
April 24th, 2008
According to recent research published in the journal Breast Cancer Research and Treatment, "Manganese superoxide dismutase (MnSOD) is known to play a role in cancer. MnSOD exerts a tumor suppressive effect in estrogen-dependent human breast cancer cells." "In the present study we investigated the in vitro role of MnSOD in the growth of some aggressive and highly metastatic estrogen-independent breast cancer cells, i.e., MDA-MB231 and SKBR3 cells. We show that estrogen-independent cells expressed a significantly higher basal MnSOD level compared to estrogen-dependent human breast cancer cell lines (MCF-7 and T47D). For MDA-MB231 cells, the high-MnSOD level was...
Source: Women's Health Weekly (2008-04-24)
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