Women's Health Weekly
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Breast Cancer
New breast cancer data have been reported by N.J. Bundred and co-authors
April 24th, 2008
According to recent research from Manchester, the United Kingdom, "Letrozole is safe and effective in postmenopausal women with estrogen receptor-positive early breast cancer, but long-term aromatase inhibitor use may cause bone loss and increase fracture risk. This study evaluated an immediate or delayed strategy of bone protection therapy with zoledronic acid." "A total of 1065 patients who were receiving adjuvant letrozole were randomized to immediate-start or delayed-start zoledronic acid (4 mg intravenously biannually for 5 years). The delayed group received zoledronic acid if lumbar spine or total hip T-score decreased below -2.0 or when a nontraumatic fracture...
Source: Women's Health Weekly (2008-04-24)
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